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张俊文

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姓名:张俊文  性别:男  职称:副教授

招生类型:科学学位(硕)

招生专业:肿瘤学(硕)

研究方向:溶瘤病毒治疗脑肿瘤基础与临床研究

电子信箱:jewzhang@hotmail.com

社会任职

个人简历

1. 202012-202309:北京市神经外科研究所 副研究员

2. 201508-202011:北京市神经外科研究所 助理研究员

3. 201209-201506:中国医学科学院医学分子生物学国家重点实验室 博士后

4. 200909-201207:清华大学北京协和医学院 博士

5. 200509-200807:首都师范大学 硕士

重要学术论文

1. Wang P#, Zhang JW#, Zhang Q, Liu F.Mesenchymal stem cells loaded with Ad5-Ki67/IL-15 enhance oncolytic adenovirotherapy in experimental glioblastoma.Biomed Pharmacother.2023.157.114035.SCI

2. Zhou X, Jin G, Zhang JW*, Liu F*.Recruitment mechanisms and therapeutic implications of tumor-associated macrophages in the glioma microenvironment.Frontiers in immunology.2023.14.1067641.SCI

3. Zhang JW, Wang J, Li M, Su X, Tian Y, Wang P, Zhou X, Jin G, Liu F*.Oncolytic HSV-1 suppresses cell invasion through downregulating Sp1 in experimental glioblastoma.Cell Signal.2023.103.110581.SCI

4. Liu S, Li M, Sun F, Zhang JW*, Liu F*.Enhancing the immune effect of oHSV-1 therapy through TLR3 signaling in uveal melanoma.J Cancer Res Clin Oncol.2023.149(2).901-912.SCI

5. Han X, Wang Q, Fang S, Wang J, Liu F, Zhang JW*, Jin G*.P4HA1 Regulates CD31 via COL6A1 in the Transition of Glioblastoma Stem-Like Cells to Tumor Endothelioid Cells.Frontiers in oncology.2022.12.836511.SCI

6. Wang Q#, Zhang JW#, Fang S, Wang J, Han X, Liu F*, Jin G*.P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization.Onco Targets Ther.2021.14.1771-1782.SCI

7. Zhang JW#, Fang S, Song W, Zhang B, Fan W, Jin G, Liu F*.Biological Characterization and Therapeutics for Subscalp Recurrent in Intracranial Glioblastoma.Onco Targets Ther.2020.13.9085-9099.SCI

8. Liu S, Liu F, Zhao M, Zhang JW*.Antitumor Efficacy of Oncolytic Herpes Virus Type 1 Armed with GM-CSF in Murine Uveal Melanoma Xenografts.Cancer Manag Res.2020.12.11803-11812.SCI

9. Fan WH#., Shao MY#., Zhang JW., Jin G. S., Xu FJ*., Liu FS*.A Hybrid Nanovector of Suicide Gene Engineered Lentivirus Coated with Bioreducible Polyaminoglycosides for Enhancing Therapeutic Efficacy against Glioma.Adv Funct Mater .2019.29(11).1807104.SCI

10. Zhang B#, Zhang JW#, Fang S, Zhang M, Liu S, Tian Y, Ma M, Liu F, Jin G*.Inflammatory activation of microglia by Staphylococcus aureus caused phenotypic alterations and affected glioblastoma growth.Cell Biochem Funct.2019.37(5).331-339.SCI

11. Zhang JW, Cui YB, Chen H, Huang BR*, Liu FS*.eIF4A1 is Associated With TrkA and Inhibits TrkA Polyubiquitination.Progress in Biochemistry and Biophysics.2019.46(8).812-822.SCI

12. Liu S#., Song W#., Liu F., Zhang JW*., Zhu S*.Antitumor efficacy of VP22-CD/5-FC suicide gene system mediated by lentivirus in a murine uveal melanoma model.Exp Eye Res.2018.172.144-151.SCI

13. Zhang JW, Cong X, Zhaoqiao J, Yang X, Li M, Chen H, Mi R, Jin G, Liu F*, Huang BR*.Ran binding protein 9 (RanBPM) binds IFN-lambdaR1 in the IFN-lambda signaling pathway.Sci China Life Sci.2017.60(9).1030-1039.SCI

14. Zhang JW., Ma W., Tian S., Fan Z., Ma X., Yang X., Zhao Q., Tan K., Chen H., Chen D, , Huang BR*.RanBPM interacts with TbetaRI, TRAF6 and curbs TGF induced nuclear accumulation of TbetaRI.Cell Signal.2014.26(1).162-172.SCI

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